Test Details
Result Turnaround Time
21 - 24 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
This test method uses a plaque reduction assay. It measures the extent to which various concentrations of acyclovir inhibit the growth of virus in cell culture. The concentration of drug which results in a 50% reduction in plaque formation induced by viral cytopathic effect (CPE) versus the no-drug control establishes an inhibitory dose (ID-50) drug concentration reportable value.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Actively-growing isolate (preferred) or eye, genital, oral, urethral, vesicle, or throat swab (from which HSV isolation will be attempted)
Volume
One cell culture tube or one swab in viral transport media
Container
Isolate growing in a permissive cell line (ie MRC-5 or A549) or primary sample in viral transport media (VTM)
Storage Instructions
Maintain isolate at room temperature. Refrigerate viral transport media with swab. Submit as soon as possible, but within five days of collection.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 138370 | HSV Acyclovir Resistance | 8-Jan | 138371 | ID 50 = | ug/mL | 8-Jan |
| Order Code | 138370 | |||||
| Order Code Name | HSV Acyclovir Resistance | |||||
| Order Loinc | 8-Jan | |||||
| Result Code | 138371 | |||||
| Result Code Name | ID 50 = | |||||
| UofM | ug/mL | |||||
| Result LOINC | 8-Jan |